Dobutamine is more commonly used to treat heart failure. When do you use LEVOPHED vs dobutamine?ĭobutamine and Levophed (norepinephrine bitartrate) are indicated to treat shock and low blood pressure (hypotension).

The same type of cardiac arrhythmias may result from the use of LEVOPHED in patients with profound hypoxia or hypercarbia. Hence, the use of LEVOPHED during cyclopropane and halothane anesthesia is generally considered contraindicated because of the risk of producing ventricular tachycardia or fibrillation. Why do we give norepinephrine in septic shock?.Which bacteria are responsible for the highest mortality rate with sepsis?.What is the black box warning for norepinephrine?.What is the difference between norepinephrine and epinephrine?.When do you use dobutamine vs dopamine?.When do you use LEVOPHED vs dobutamine?.It is not known if norepinephrine is excreted into breast milk avoid use during breastfeeding.Animal studies show risk and human studies are not available or neither animal nor human studies were done. Use norepinephrine with caution during pregnancy if the benefits outweigh the risks.Extreme caution in concurrent monoamine oxidase inhibitor ( MAOI) use.Sulfite allergy due to the presence of metabisulfite.Mesenteric or peripheral vascular thrombosis.See 'What Are Side Effects Associated with Using Norepinephrine?'.Concomitant use with some general anesthetics: Chloroform, trichloroethylene, cyclopropane, halothane.Peripheral vascular thrombosis (except for lifesaving procedures).Low blood pressure (hypotension) due to blood volume deficit.In case of overdose, get medical help or contact a Poison Control Center immediately. Do not take Levarterenol or Levophed if you are allergic to norepinephrine or any ingredients contained in this drug. This medication contains norepinephrine.Use a syringe with a fine hypodermic needle, with the solution being infiltrated liberally throughout the area, which is easily identified by its cold, hard, pallid appearance.Antidote for extravasation ischemia: To prevent sloughing and necrosis in areas where extravasation has taken place, infiltrate areas promptly with 10-15 mL of saline solution containing 5-10 mg of phentolamine mesylate for injection.What Are Warnings and Precautions for Norepinephrine? Warnings Check with your physician if you have health questions or concerns. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. This document does not contain all possible interactions. Mild Interactions of norepinephrine include:.Norepinephrine has moderate interactions with at least 261 different drugs.Norepinephrine has serious interactions with at least 34 different drugs.Severe interactions of norepinephrine include:.Do not start, stop, or change the dosage of this medicine or any medicine before getting further information from your doctor, healthcare provider, or pharmacist first. If your doctor has directed you to use this medication for your condition, your doctor or pharmacist may already be aware of any possible drug interactions or side effects and may be monitoring you for them. What Other Drugs Interact with Norepinephrine? You may report side effects to FDA at 1-80. Call your doctor for information and medical advice about side effects. This is not a complete list of side effects and other serious side effects may occur. Dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, irregular heartbeats, seizure).Urinating less than usual or not at all.

Sudden numbness/weakness/cold feeling in your body.

Pain or burning where the injection is given.

Serious side effects of norepinephrine include:

Redness and swelling at the injection site.

Shortness of breath, with or without respiratory difficulty.

What Are Side Effects Associated with Using Norepinephrine?Ĭommon side effects of norepinephrine include:

SLIDESHOW Low Blood Pressure (Hypotension): Symptoms, Signs, Causes See Slideshow Tricyclic Antidepressant Toxicity (Off-label) Should be titrated to age-appropriate blood pressureĬalcium Channel Blocker Toxicity (Off-label).Pediatric: 0.05-0.1 mcg/kg/minute IV infusion titrate to effect not to exceed 2 mcg/kg/minute.Adult: 0.01-3 mcg/kg/minute intravenous (IV) infusion.Initial: 0.05-0.1 mcg/kg/minute intravenous (IV) infusion titrate to effect.Maintenance: 2-4 mcg/minute IV infusion.Initial: 8-12 mcg/minute intravenous (IV) infusion titrate to effect.What Are Dosages of Norepinephrine? Dosages of Norepinephrine:Īdult and Pediatric Dosage Forms and Strengthsĭosage Considerations – Should be Given as Follows:

Levophed drip